@phaedrux Thanks for the help but I figured it out.
I deleted the printers profile in S3D and re-entered it and now it works.

@tinfish340 SOLVED!!!!!!!!!!!!!!!

Some help would be nice. Thanks.

Changed to a new extruder hotend combo. I don't think this is related to the issues at all since it works
exactly as it should.
The machine has sat for several months without use. I get everything installed and the homing is totally
messed up. Tried everything I know and still no change.
I upgraded to Firmware 3.3 to see if this helped. No change except now when I hit emergency stop
it will not reset unless I shut off the machine, close out the web page and then restart everything.
I can home everything fine. Then I move to the center of the bed to do the G30 S-1 to calibrate
the sensor to enter it into the G31 config.g file. That also works, but then when I hit save it resets all of the
tool positions to 0.
If I home everything again and then run mesh compensation that woks as it should and finishes up
at the left rear corner. If I hit home all, it comes back to the center of the bed instead of the left front
corner and then proceeds to drive the Z axes into the bed. I think the tool position reads -375 at that point
and I have to hit emergency stop.
Also if I home everything and then move X,Y and Z to different positions to see if home all works correctly
it will lift Z up a little and then down a little and reset all the tool positions to 0.
Duet 2 wifi, carteasan printer, optical sensors, TH3D Z probe. I also created a new configuration file to no avail.

; Configuration file for Duet WiFi (firmware version 3.3)
; executed by the firmware on start-up
;
; generated by RepRapFirmware Configuration Tool v3.3.2 on Mon Sep 27 2021 15:49:04 GMT-0700 (Pacific Daylight Time)

; General preferences
M575 P1 S1 B57600                                      ; enable support for PanelDue
G90                                                    ; send absolute coordinates...
M83                                                    ; ...but relative extruder moves
M550 P"Black Widow"                                    ; set printer name

; Network
M552 S1                                                ; enable network
M586 P0 S1                                             ; enable HTTP
M586 P1 S0                                             ; disable FTP
M586 P2 S0                                             ; disable Telnet

; Drives
M569 P0 S1                                             ; physical drive 0 goes forwards
M569 P1 S1                                             ; physical drive 1 goes backwards
M569 P2 S0                                             ; physical drive 2 goes backwards
M569 P3 S0                                             ; physical drive 3 goes backwards - Extruder
M584 X0 Y1 Z2 E3                                       ; set drive mapping
M350 X16 Y16 Z16 E16 I1                                ; configure microstepping with interpolation
M92 X160.00 Y800.00 Z1600.00 E409.00                   ; set steps per mm
M566 X600.00 Y420.00 Z12.00 E118.00                    ; set maximum instantaneous speed changes (mm/min)
M203 X6000.00 Y6000.00 Z500.00 E400.00                 ; set maximum speeds (mm/min)
M201 X1000.00 Y1000.00 Z200.00 E250.00                 ; set accelerations (mm/s^2)
M906 X1600 Y1600 Z900 E1000 I30                        ; set motor currents (mA) and motor idle factor in per cent
M84 S30                                                ; Set idle timeout

; Axis Limits
M208 X0 Y0 Z0 S1                                       ; set axis minima
M208 X370 Y365 Z375 S0                                 ; set axis maxima

; Endstops
M574 X1 S1 P"xstop"                                    ; configure active-high endstop for high end on X via pin xstop
M574 Y1 S1 P"ystop"                                    ; configure active-high endstop for high end on Y via pin ystop
M574 Z0 P"nil"                                         ; no Z endstop switch, free up Z endstop input
M564 S0 H0

; Z-Probe
M558 P5 C"^!zprobe.in" H10 F120 T6000                  ; set Z probe type to unmodulated and the dive height + speed
G31 P100 X40 Y7 Z1.9                                   ; set Z probe trigger value, offset and trigger height
M557 X15:300 Y15:360 S20                               ; define mesh grid

; Heaters
M308 S0 P"bed_temp" Y"thermistor" T100000 B3950        ; configure sensor 0 as thermistor on pin bedtemp
M950 H0 C"bedheat" T0                                  ; create bed heater output on bedheat and map it to sensor 0
M307 H0 B0 S1.00                                       ; disable bang-bang mode for the bed heater and set PWM limit
M140 H0                                                ; map heated bed to heater 0
M143 H0 S120                                           ; set temperature limit for heater 0 to 120C
M308 S1 P"e0temp" Y"thermistor" T100000                ; configure sensor 1 as thermistor on pin e0temp
M950 H1 C"e0heat" T1                                   ; create nozzle heater output on e0heat and map it to sensor 1
M307 H1 B0 S1.00                                       ; disable bang-bang mode for heater  and set PWM limit
M143 H1 S280                                           ; set temperature limit for heater 1 to 280C

; Fans
M950 F0 C"fan0" Q500                                   ; create fan 0 on pin fan0 and set its frequency
M106 P0 S0 H-1                                         ; set fan 0 value. Thermostatic control is turned off
M950 F1 C"fan1" Q500                                   ; create fan 1 on pin fan1 and set its frequency
M106 P1 S1 H-1                                         ; set fan 1 value. Thermostatic control is turned off

; Tools
M563 P0 D0 H1 F0                                       ; define tool 0
G10 P0 X0 Y0 Z0                                        ; set tool 0 axis offsets
G10 P0 R0 S0                                           ; set initial tool 0 active and standby temperatures to 0C

; Custom settings are not defined

; Miscellaneous
M501                                                   ; load saved parameters from non-volatile memory
M911 S10 R11 P"M913 X0 Y0 G91 M83 G1 Z3 E-5 F1000"     ; set voltage thresholds and actions to run on power loss

; homeall.g
; called to home all axes
;
; generated by RepRapFirmware Configuration Tool on Sat Mar 04 2017 15:46:00 GMT+0100 (W. Europe Standard Time)

; Relative positioning
G91                                   ; Lift Z
G1 Z5 F6000                           ; Course home X and Y
G1 X-235 Y-215 F4000 H1               ; Move away from the endstops
G1 X5 Y5 F5000                        ; Fine home X and Y
G1 X-235 Y-215 F250 H1                ; Absolute positioning
G90                                   ; Go to first bed probe point and home Z
T0                                    ; select first hot end
G91                                   ; Relative coordinates
G1 Z3 F200                            ; Lower bed to avoid hotend dragging in bed.
G90                                   ; Absoulte coordinates
G1 X160 Y125 F3000                    ; Go to first bed probe point and home the Z axis
G1 Z2 F200                            ; Raise bed to 2mm.

; homex.g
; called to home the X axis
;
; generated by RepRapFirmware Configuration Tool v3.1.10 on Mon Dec 14 2020 20:24:29 GMT-0800 (Pacific Standard Time)
G91               ; relative positioning
G1 H2 Z5 F6000    ; lift Z relative to current position
G1 H1 X-375 F1800 ; move quickly to X axis endstop and stop there (first pass)
G1 H2 X5 F6000    ; go back a few mm
G1 H1 X-375 F360  ; move slowly to X axis endstop once more (second pass)
G1 H2 Z-5 F6000   ; lower Z again
G90               ; absolute positioning

; homey.g
; called to home the Y axis
;
; generated by RepRapFirmware Configuration Tool v3.3.2 on Mon Sep 27 2021 15:49:05 GMT-0700 (Pacific Daylight Time)
G91              ; relative positioning
G1 H2 Z5 F6000   ; lift Z relative to current position
G1 H1 Y370 F1800 ; move quickly to Y axis endstop and stop there (first pass)
G1 H2 Y-5 F6000  ; go back a few mm
G1 H1 Y370 F360  ; move slowly to Y axis endstop once more (second pass)
G1 H2 Z-5 F6000  ; lower Z again
G90              ; absolute positioning

; homez.g
; called to home the Z axis
;
; generated by RepRapFirmware Configuration Tool v3.3.2 on Mon Sep 27 2021 15:49:05 GMT-0700 (Pacific Daylight Time)
G91               ; relative positioning
G1 H2 Z5 F6000    ; lift Z relative to current position
G90               ; absolute positioning
G1 X45 Y25 F6000  ; go to first probe point
G30               ; home Z by probing the bed

; Uncomment the following lines to lift Z after probing
;G91               ; relative positioning
;G1 Z5 F100       ; lift Z relative to current position
;G90              ; absolute positioning

Gulfcoast Robotics 100K NTC 3950 - M3 Stud Screw-in thermistor and
I have also tried, not sure of the brand, NTC 3950 100K Thermistor with the glass end.

Duet WiFi Server Version: 1.23

This printer is a highly modified Black Widow that I have been using for years. Not much Black Widow left but these are the original settings. These settings have worked for a very long time until now. I also came up with the same settings when using the configurator. But I am open to anything that will get this working again.

So apparently that did not fix the problem. It did go up to 270C with no problems but upon printing there was almost no bonding between layers. The whole print just came apart. I feel like the problem lies within the board. How do you go from a perfectly good printer to junk when absolutely nothing changed as far as code goes? It will struggle to reach 210C now with no errors no matter how long it takes to get there.

FYI, I am using this. Flexion Dual Extruder

Changed that around and ran PID auto tune and that fixed it.
Thanks for your help!!!

@Phaedrux Error: Heating fault on heater 1, temperature rising much more slowly than the expected 0.4°C/sec.

; Configuration file for Duet WiFi (firmware version 1.21)
; executed by the firmware on start-up
;
; generated by RepRapFirmware Configuration Tool v2 on Fri Mar 29 2019 23:01:22 GMT-0700 (Pacific Daylight Time)

; General preferences
M111 S0 ; Debugging off
G21 ; Work in millimetres
G90 ; Send absolute coordinates...
M83 ; ...but relative extruder moves
M555 P2 ; Set firmware compatibility to look like Marlin
M208 X0 Y0 Z0 S1 ; Set axis minima
M208 X330 Y300 Z375 S0 ; Set axis maxima

; Endstops
M574 X1 Y1 Z1 S0 ; Define active low and unused endstops
M558 P5 X0 Y0 Z1 H5 F200 T6000 ; Set Z probe type to analog, the axes for which it is used and the probe + travel speeds
G31 X40 Y7 Z0.9 P50 ; Set Z probe trigger value, offset and trigger height

				;Z-offset (Z0.9). Higher value LOWER nozzle height					
				;	   Lower value RAISE nozzle height

M557 X10:340 Y10:240 S68 ; Define mesh grid
M564 S0 H0

; Drives
M569 P0 S1 ; Drive 0 goes forwards - X
M569 P1 S1 ; Drive 1 goes backwards - Y
M569 P2 S0 ; Drive 2 goes backwards - Z
M569 P3 S1 ; Drive 3 goes forwards - Extruder

M350 X16 Y16 Z16 E16 I1 ; Configure microstepping with interpolation 16
M92 X160 Y800 Z1600 E90 ; Set steps per mm 16

M566 X600 Y420 Z12 E120 ; Set maximum instantaneous speed changes (mm/min) - (JERK)

M203 X6000 Y6000 Z500 E400 ; Set maximum speeds (mm/min)

M201 X1000 Y1000 Z200 E250 ; Set accelerations (mm/s^2)

M204 P1000 T1000 ; Set Max acceleration for P=printing moves and T=travel moves
M906 X1600 Y1600 Z900 E1000 I30 ; Set motor currents (mA) and motor idle factor in per cent
M84 S30 ; Set idle timeout

; Heaters
M143 S285 ; Set maximum heater temperature to 285C
;M305 P1 X101

M305 P1 T107000 B10832 C4.891620e-7 R4700 ; Set thermistor + ADC parameters for heater 0 - BED
M305 P0 T99600 B4388 C0 R4700 ; Set thermistor + ADC parameters for heater 1 - HOTEND E3d

M307 H0 P96.0, I3.285, D603.9 ;Bed
;M307 H1 P1.1, I0.011, D51.5 ;Hotend pid

M307 H1 P17.8, I0.055, D74.9 ;Hotend E3d pid

; Tools
M563 P0 D0 H1 ; Define tool 0
G10 P0 X0 Y0 Z0 ; Set tool 0 axis offsets
G10 P0 R0 S0 ; Set initial tool 0 active and standby temperatures to 0C

; Network
M550 P"Black Widow" ; Set machine name
M552 S1 ; Enable network
M586 P0 S1 ; Enable HTTP
M586 P1 S0 ; Disable FTP
M586 P2 S0 ; Disable Telnet

; Fans
M106 P0 S0.3 I0 F500 H-1 ; Set fan 0 value, PWM signal inversion and frequency. Thermostatic control is turned off
M106 P1 S1 I0 F500 H1 T45 ; Set fan 1 value, PWM signal inversion and frequency. Thermostatic control is turned on
M106 P2 S1 I0 F500 H1 T45 ; Set fan 2 value, PWM signal inversion and frequency. Thermostatic control is turned on

M501

; Automatic saving after power loss is not enabled

; Custom settings are not configured!

@Danal No. Nothing has changed. I have done 60+ hour prints with this
setup. That is what is baffling me. Power at the hot end maintains 24v.

16.5 hours into a 17 hour print at 260c when the hotend plugged up.
Fixed that and now I get a heater error at 177c. Replaced thermister and heater cartridge twice. No change. Checked all wiring. OK and everything ohm's out correctly.
Ran PID and still errors at 177c. I increased the dead time to no avail.
Everything has been running fine until now.
Ver 1.23
Any help is appreciated.