@Ret as already said. You should change your micro stepping to 1/32 at the max. No FFF printer will have any better results going higher. Also, change your steps/mm. If you are using pressure advance turn it off. You really need a good tune on your extruder before you ever mess with pressure advance.
Your accelerations for movement on axis is high but very low for your extruder. I have a different printer but you might want to try my settings.
M566 X750 Y750 Z90 E1200 ; Set maximum instantaneous speed changes (mm/min)
M203 X18000 Y18000 Z6000 E9000 ; Set maximum speeds (mm/min)
M201 X1800 Y1800 Z250 E10000 ; Set accelerations (mm/s^2)
With a "Jerk" of 1mm/s on your extruder, you are going to have crazy strange stuff happening especially if you are using pressure advance. I would expect massive pauses on small circle/arcs. I actually complained about PA a while back but it was all in my tuning. I was having what you are but not to your extent.
You might not want to use my Z settings as I know for a fact you have a completely different setup for your z than I do. You might not try this but honestly, it's probably the few things jamming you up.
Also, I used to use S3D exclusively. Now I only use Cura 3.2.1+. But that requires a lot more tuning and tweaking of settings. S3D makes a lot of garbage code but it's easy to use and gives very good top layers. Make these changes and if your problems go away then you can start doing more tuning. Maybe give Cura a try. It's given me much better control over my prints and produced astonishing print quality. Best of luck.